Article
[Genetics and cancer: fundamental and clinical aspects].
Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique - 1 Nov 2001
Soussi T
Abstract excerpt
The twentieth century has witnessed the discovery of the various genetic alterations that drive a normal cell toward neoplasia. One the challenge of the near future concerns the diagnostic of these alterations and their correlation with clinical parameters such as response to therapy or survival. It will be important to define, for each patient, a specific profile of the various alterations in order to improve...
Topics
- Apoptosis
- Cell Cycle
- Cell Transformation, Neoplastic
- Genes, Tumor Suppressor
- Genetic Predisposition to Disease
- Genotype
- Humans
- Neoplasms
- Oncogenes
- Phenotype
- Predictive Value of Tests
- Prognosis
- Treatment Outcome
