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Article

Hereditary common cancers: molecular and clinical genetics.

Anticancer research - 1 Jan 2000

Russo A, Zanna I, Tubiolo C, Migliavacca M, Bazan V, Latteri M A, Tomasino R M, Gebbia N

Abstract excerpt

This review focuses on the functional role and structural features of the genes involved in common hereditary cancers. Most of these tumors are sporadic and the genetic alterations responsible for their genesis take place over several cell generations; nevertheless, 5 to 10% of the human tumors are hereditary, with a rapid development. Cancer susceptibility genes have been classified as "gatekeepers" (e.g. RB1,...

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Identifiers

PMID: 11205230

Genes

BRCA1
APC
BRCA2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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