Article
N-terminal characterization of the Bordetella pertussis filamentous haemagglutinin.
Molecular microbiology - 1 Jun 1998
Lambert-Buisine C, Willery E, Locht C, Jacob-Dubuisson F
Abstract excerpt
The major adhesin of Bordetella pertussis, filamentous haemagglutinin (FHA), is produced and secreted at high levels by the bacterium. Mature FHA derives from a large precursor, FhaB, that undergoes several post-translational maturations. In this work, we demonstrate by site-directed mutagenesis...
Topics
- Adhesins, Bacterial
- Amino Acid Sequence
- Amino Acid Substitution
- Artificial Gene Fusion
- Bordetella pertussis
- Codon, Initiator
- Hemagglutinins
- Molecular Sequence Data
- Mutagenesis, Site-Directed
- Mutation
- Protein Sorting Signals
- Sequence Deletion
- Virulence Factors, Bordetella