Synthetic human antibodies and a strategy for protein engineering.

doi:10.1016/s0014-5793(98)00628-0

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Article

Synthetic human antibodies and a strategy for protein engineering.

FEBS letters - 23 Jun 1998

Winter G

Abstract excerpt

Our understanding of the way antibodies are built in vivo has provided an approach for engineering synthetic human antibodies in bacteria. Such antibodies have not only been raised against foreign antigens, but also against highly conserved antigens or human self-antigens, and have considerable p...

Topics

Antibodies
Antibody Formation
Humans
Mutation
Protein Engineering
Recombinant Proteins

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