Article
Relation between severity of coronary artery disease, left ventricular function and myocardial infarction, and influence of the ACE I/D gene polymorphism.
The American journal of cardiology - 15 Jul 1998
Ledru F, Blanchard D, Battaglia S, Jeunemaitre X, Courbon D, Guize L, Guermonprez J L, Ducimetière P, Diébold B
Abstract excerpt
Left ventricular (LV) systolic function is partly determined by severity of coronary artery disease and is improved by angiotensin-converting enzyme (ACE) inhibition, at least in post-infarct patients. Because the ACE insertion/deletion (I/D) gene polymorphism is associated with circulating and t...
Topics
- Aged
- Angiotensin-Converting Enzyme Inhibitors
- Confounding Factors, Epidemiologic
- Coronary Angiography
- Coronary Disease
- Female
- Genotype
- Humans
- Male
- Middle Aged
- Myocardial Infarction
- Polymorphism, Genetic
- Severity of Illness Index
- Stroke Volume