Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A sex-specific difference in homozygosity for HLA-DR53 in newborns.

The Turkish journal of pediatrics - 1 Jan 2000

Sunguroğlu A, Güç D, Sipahi T U, Dorak M T

Abstract excerpt

Homozygosity for HLA-DR53 confers increased susceptibility to major forms of leukemia. In childhood leukemia, this influence is male-specific. Two separate studies have shown a male-specific increase in the homozoygosity rate for HLA-DR53 in healthy adults. This finding was attributed to possible preferential transmission of HLA-DR53 towards male offspring. If this is the case, the consequences of such a prenatal...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Gene Frequency
Share to Genetic Predisposition to Disease
Share to Genotype

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to HLA-DR Antigens

Share to Homozygote

Share to Infant, Newborn

Share to Polymorphism, Restriction Fragment Length

Share to Selection, Genetic

Source

Identifiers

PMID: 9677726

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 8 closest

A sex-specific difference in homozygosity for HLA-DR53 in newborns.PMID 9677726Read ↗

A male-specific increase in the HLA-DRB4 (DR53) frequency in high-risk and relapsed childhood ALL.Semantic proximity Read ↗

No gender differences in the frequencies of HLA-DRB3/B4/B5 heterozygotes in newborns and adults in Koreans.Semantic proximity Read ↗

Nature of HLA-associated predisposition to childhood acute lymphoblastic leukemia.Semantic proximity Read ↗

Increased heterozygosity for MHC class II lineages in newborn males.Semantic proximity Read ↗

Unravelling an HLA-DR association in childhood acute lymphoblastic leukemia.Semantic proximity Read ↗

Examination of genetic polymorphisms in newborns for signatures of sex-specific prenatal selection.Semantic proximity Read ↗

Compound heterozygosity of HLA-DRB3*01:01 and HLA-DRB4*01:01 as a potential predictor of fetal neonatal alloimmune thrombocytopenia.Semantic proximity Read ↗

Evidence that an HLA-DQA1-DQB1 haplotype influences susceptibility to childhood common acute lymphoblastic leukaemia in boys provides further support for an infection-related aetiology.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.