Article
Clinical experience with famciclovir against hepatitis B virus.
Intervirology - 1 Jan 1997
Bartholomeusz A, Groenen L C, Locarnini S A
Abstract excerpt
Famciclovir (FCV, the oral form of penciclovir, PCV) is a potent antiviral agent of hepatitis B virus (HBV) and is currently in phase III clinical trials. In this review, we examine the outcome of FCV treatment in preventing recurrent HBV in patients post transplantation. Resistance to FCV has now been documented in this setting, in which reduced sensitivity to FCV was associated with mutations upstream from the...
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