Article
Kinetic properties and thermal stabilities of mutant forms of mitochondrial aspartate aminotransferase.
Biochimica et biophysica acta - 28 Jul 1998
Azzariti A, Vacca R A, Giannattasio S, Merafina R S, Marra E, Doonan S
Abstract excerpt
Kinetic properties and thermal stabilities of the precursor form of mitochondrial aspartate aminotransferase, the mature form lacking 9 amino acids from the N-terminus, and forms of the mature protein in which cysteine-166 had been mutated to serine or alanine were compared with those of the mature enzyme. The precursor and the cysteine mutants showed moderately impaired catalytic properties consistent with...
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