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Article

A Perspective on the Control of Mammalian Fertilization by Egg-Activated Ion Channels in Sperm: A Tale of Two Channels1

1 Jul 1998

Abstract excerpt

Mammalian sperm contain a single large secretory vesicle, or acrosome. Exocytosis of this vesicle (the acrosome reaction) occurs as an early step in the gamete interaction process and is an essential prerequisite for late events, including sperm-egg fusion [1]. The control of fertilization is, from this perspective, a question of the regulation of a secretory event. It may be useful to compare sperm to other...

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PMID: 9674987
DOI: 10.1095/biolreprod59.1.12

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