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Article

Dynamic resolution of acrosomal exocytosis in human sperm

4 Jun 2008

Abstract excerpt

An essential step in mammalian fertilisation is the sperm acrosome reaction (AR) - exocytosis of a single large vesicle (the acrosome) that surrounds the nucleus at the apical sperm head. The acrosomal and plasma membranes fuse, resulting in both the release of factors that might facilitate penetration of the zona pellucida (which invests the egg) and the externalisation of membrane components required for gamete...

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PMID: 18522990
DOI: 10.1242/jcs.030379

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