Article
Endothelial nitric oxide synthase gene is positively associated with essential hypertension.
Hypertension (Dallas, Tex. : 1979) - 1 Jul 1998
Miyamoto Y, Saito Y, Kajiyama N, Yoshimura M, Shimasaki Y, Nakayama M, Kamitani S, Harada M, Ishikawa M, Kuwahara K, Ogawa E, Hamanaka I, Takahashi N, Kaneshige T, Teraoka H, Akamizu T, Azuma N, Yoshimasa Y, Yoshimasa T, Itoh H, Masuda I, Yasue H, Nakao K
Abstract excerpt
Essential hypertension has a genetic basis. Accumulating evidence, including findings of elevation of arterial blood pressure in mice lacking the endothelial nitric oxide synthase (eNOS) gene, strongly suggests that alteration in NO metabolism is implicated in hypertension. There are, however, no...
Topics
- Adult
- Aged
- Alleles
- Base Sequence
- Confidence Intervals
- Data Interpretation, Statistical
- Endothelium, Vascular
- Exons
- Female
- Gene Frequency
- Genotype