Article
Positive association of endothelial nitric oxide synthase gene polymorphism with hypertension in northern Japan.
Life sciences - 19 May 2000
Shoji M, Tsutaya S, Saito R, Takamatu H, Yasujima M
Abstract excerpt
Vascular endothelial cells produce nitric oxide (NO), which contributes to the regulation of blood pressure and regional blood flow. Although Endothelial NO synthase (eNOS) gene polymorphisms have been shown to have a positive association with coronary artery disease, the linkage between eNOS gene polymorphisms and hypertension has been controversial. In the present study, therefore, we identified genotypes for...
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