Article
Gender specific association of endothelial nitric oxide synthase gene (Glu298Asp) polymorphism with essential hypertension in a south Indian population.
Clinica chimica acta; international journal of clinical chemistry - 1 Sept 2008
Periaswamy Ramu, Gurusamy Umamaheswaran, Shewade Deepak Gopal, Cherian Akkarapatty, Swaminathan Rathinam Palamalai, Dutta Tarun Kumar, Jayaraman Balachander, Chandrasekaran Adithan
Abstract excerpt
BACKGROUND: Endothelial derived nitric oxide (NO) plays a major role in blood pressure regulation. The role of missense variant eNOS-Glu298Asp has been demonstrated by many studies with conflicting results. Our objective was to investigate the association of eNOS gene polymorphism with essential hypertension in a south Indian population. METHODS: We carried out a case control study in 438 hypertensive patients...
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