Article
Production of stabilized virulence factor-negative variants by group A streptococci during stationary phase.
Infection and immunity - 1 Aug 1998
Leonard B A, Woischnik M, Podbielski A
Abstract excerpt
Many of the virulence factors associated with fulminant group A streptococci (GAS) infection are expressed under in vitro exponential growth conditions. However, the survival of GAS in tissue and intracellularly, as well as colonization of asymptomatic carriers, has been reported for GAS. The bacteria associated with these niches may encounter high-density, low-nutrient-flowthrough conditions that may more...
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