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Article

Oxygen-dependent phenotypic variation in group A streptococcus.

Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi - 1 Dec 2016

Chiang-Ni Chuan, Nian Siao-Ying, Wu Jiunn-Jong, Chen Chih-Jung

Abstract excerpt

BACKGROUND: The phenotypic heterogeneity of the human pathogen Streptococcus pyogenes [group A streptococcus (GAS)] is associated with bacterial virulence variation. During invasive GAS infection, mutations in the two-component regulatory system covR/covS leads to increases in hyaluronic acid capsule production, virulence genes expression, and lethality in the mouse infection model. Phenotypic variation of GAS is...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 25649484
DOI: 10.1016/j.jmii.2014.11.010

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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