Article
Bovine hemoglobin alpha-globin chain polymorphism: primary structure determination of two new genetic variants by mass spectrometry and amino acid sequencing.
Biochimie - 1 Apr 1998
Scaloni A, Pieragostini E, Malorni A, Ferrara L, Di Luccia A
Abstract excerpt
The present work describes the biochemical procedures used to identify the cause of a quantitative and qualitative hemoglobin polymorphism found in Podolian cattle. First, to analyze the different phenotypes, isoelectric focusing (IEF) of hemoglobins and RP-HPLC of globin chains was carried out;...
Topics
- Amino Acid Sequence
- Animals
- Bison
- Cattle
- Chromatography, High Pressure Liquid
- Genetic Variation
- Globins
- Hemoglobins
- Macromolecular Substances
- Mass Spectrometry
- Molecular Sequence Data
- Polymorphism, Genetic
- Ruminants
- Sequence Alignment
- Sequence Homology, Amino Acid
- Species Specificity