Article
Interferon therapy in LKM-1 positive patients with chronic hepatitis C: follow-up by a quantitative radioligand assay for CYP2D6 antibody detection.
Journal of hepatology - 1 Jun 1998
Duclos-Vallée J C, Nishioka M, Hosomi N, Arima K, Leclercq A, Bach J F, Yamamoto A M
Abstract excerpt
BACKGROUND/AIMS: Liver/kidney microsomal type 1 (LKM-1) antibodies described by indirect immunofluorescence using frozen sections of kidney, stomach and rat liver define a group of patients with type 2 autoimmune hepatitis. Sera react with a non-glycosylated 50-kD protein of the endoplasmic retic...
Topics
- Adult
- Alanine Transaminase
- Animals
- Antiviral Agents
- Autoantibodies
- Cytochrome P-450 CYP2D6
- Female
- Fluorescent Antibody Technique, Indirect
- Follow-Up Studies
- Genotype
- HLA-DR Antigens
- Hepacivirus
- Hepatitis C, Chronic
- Histocompatibility Antigens Class I
- Humans
- Interferons
- Male
- Middle Aged
