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Article

Clinical associations and potential novel antigenic targets of autoantibodies directed against rods and rings in chronic hepatitis C infection.

BMC gastroenterology - 19 Mar 2013

Stinton Laura M, Myers Robert P, Coffin Carla S, Fritzler Marvin J

Abstract excerpt

BACKGROUND: Chronic hepatitis C virus (HCV) infection is frequently associated with extrahepatic autoimmune disorders while interferon (IFN) and ribavirin treatment may exacerbate these conditions. Autoantibodies from HCV patients identify a novel indirect immunofluorescence (IIF) pattern on HEp-2 cells characterized by cytoplasmic rods and rings (RR). Our objectives were to determine the prevalence and clinical...

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Share to Fluorescent Antibody Technique, Indirect

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Liver Cirrhosis, Biliary

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Source

Open in PubMed Open full text

Identifiers

PMID: 23506439
DOI: 10.1186/1471-230X-13-50
PMCID: PMC3606316

Genes

CTPS1
IMPDH2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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