Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Disruption of retinoid-related orphan receptor beta changes circadian behavior, causes retinal degeneration and leads to vacillans phenotype in mice.

The EMBO journal - 15 Jul 1998

André E, Conquet F, Steinmayr M, Stratton S C, Porciatti V, Becker-André M

Abstract excerpt

The orphan nuclear receptor RORbeta is expressed in areas of the central nervous system which are involved in the processing of sensory information, including spinal cord, thalamus and sensory cerebellar cortices. Additionally, RORbeta localizes to the three principal anatomical components of the mammalian timing system, the suprachiasmatic nuclei, the retina and the pineal gland. RORbeta mRNA levels oscillate in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chromosome Mapping
Share to Circadian Rhythm

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Mice, Transgenic

Share to Phenotype

Share to Rats, Sprague-Dawley

Share to RNA, Messenger

Source

Open in PubMed Open full text

Identifiers

PMID: 9670004
DOI: 10.1093/emboj/17.14.3867
PMCID: PMC1170722

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Disruption of retinoid-related orphan receptor beta changes circadian behavior, causes retinal degeneration and leads to vacillans phenotype in mice.PMID 9670004Read ↗

An allelic series of spontaneous mutations in Rorb cause a gait phenotype, retinal abnormalities, and transcriptomic changes relevant to human neurodevelopmental conditionsSemantic proximity Read ↗

An allelic series of spontaneous Rorb mutant mice exhibit a gait phenotype, changes in retina morphology and behavior, and gene expression signatures associated with the unfolded protein response.Semantic proximity Read ↗

Retinoid-Related Orphan Receptors (RORs): Critical Roles in Development, Immunity, Circadian Rhythm, and Cellular MetabolismSemantic proximity Read ↗

The ROR nuclear orphan receptor subfamily: critical regulators of multiple biological processes.Semantic proximity Read ↗

Compromised striatal structure and function in mouse models of RARB-related disorderSemantic proximity Read ↗

staggerer phenotype in retinoid-related orphan receptor alpha-deficient mice.Semantic proximity Read ↗

An isoform of retinoid-related orphan receptor β directs differentiation of retinal amacrine and horizontal interneurons.Semantic proximity Read ↗

The nuclear receptor transcription factor, retinoid-related orphan receptor beta, regulates retinal progenitor proliferation.Semantic proximity Read ↗

High amplitude phase resetting in rev-erbalpha/per1 double mutant mice.Semantic proximity Read ↗

Core-clock genes Period 1 and 2 regulate visual cascade and cell cycle components during mouse eye development.Semantic proximity Read ↗

ROR-Family Receptor Tyrosine Kinases.Semantic proximity Read ↗

Minireview: the role of nuclear receptors in photoreceptor differentiation and disease.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.