Article
Modelling human sperm-egg interactions in vitro: signal transduction pathways regulating the acrosome reaction
1 May 1998
Abstract excerpt
Recent advances in characterizing sperm surface receptors and ion channels, when combined with the rapidly expanding knowledge of interactions among second messenger systems in somatic cells, permit formulation of a tentative molecular mechanism for the regulation of the human sperm acrosome reaction. As spermatozoa pass through the cumulus mass, progesterone binds to its sperm surface receptor, alkalinizes the...
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