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Article

Nongenomic effects of progesterone on spermatozoa mechanisms of signal transduction and clinical implications

1 Jan 1998

Abstract excerpt

Progesterone (P) is one of the physiological stimuli of human sperm acrosome reaction. It is present in high levels at the site of fertilization (cumulus oophorus) and has been describe to affect several sperm functions including motility, capacitation and acrosome reaction. The effects of the steroid, which is present in high levels in the cumulus matrix that surrounds the oocyte, are mediated by an increase of...

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PMID: 9792892
DOI: 10.2741/a345

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