Abnormal cornified cell envelope formation in mutilating palmoplantar keratoderma unrelated to epidermal differentiation complex.

doi:10.1046/j.1523-1747.1998.00230.x

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Article

Abnormal cornified cell envelope formation in mutilating palmoplantar keratoderma unrelated to epidermal differentiation complex.

The Journal of investigative dermatology - 1 Jul 1998

Akiyama M, Christiano A M, Yoneda K, Shimizu H

Abstract excerpt

Mutilating palmoplantar keratoderma represents a heterogeneous group of disorders, unified by characteristic mutilation of the fingers or toes, associated with palmoplantar keratoderma. Although loricrin gene mutations were recently reported in Vohwinkel's syndrome and erythrokeratoderma, the gen...

Topics

Adult
Cell Differentiation
Chromosomes, Human, Pair 1
Epidermis
Female
Filaggrin Proteins
Humans
Keratoderma, Palmoplantar
Male
Membrane Proteins
Mutation

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