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Article

Keratinization Disorders and Genetic Aspects in Palmar and Plantar Keratodermas.

Acta dermatovenerologica Croatica : ADC - 1 Jun 2016

Stypczyńska Ewa, Placek Waldemar, Zegarska Barbara, Czajkowski Rafał

Abstract excerpt

Palmoplantar keratoderma (PPK) is a heterogeneous group of hereditary and acquired disorders characterized by abnormal thickening of the palms and soles. There are three clinical patterns: diffuse, focal, and punctuate. Palmoplantar keratodermas can be divided into the following functional subgroups: disturbed gene functions in structural proteins (keratins), cornified envelope (loricrin, transglutaminase),...

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PMID: 27477171

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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