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Article

Modulation of the Human Homeobox Genes PRX-2 and HOXB13 in Scarless Fetal Wounds

1 Jul 1998

Abstract excerpt

Scarless healing of cutaneous wounds occurs in humans during the first two trimesters of development, but by birth all wounds are repaired with scar formation. To search for transcriptional regulatory genes that might mediate fetal tissue regeneration, we surveyed homeobox gene expression in proliferating fetal fibroblasts and in wounded and unwounded skin. Two novel human homeobox genes, PRX-2 and HOXB13, were...

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PMID: 9665387
DOI: 10.1046/j.1523-1747.1998.00238.x

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