Mild acid stress as a differentiation trigger in Trypanosoma brucei.

doi:10.1016/s0166-6851(98)00046-2

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Article

Mild acid stress as a differentiation trigger in Trypanosoma brucei.

Molecular and biochemical parasitology - 1 Jun 1998

Rolin S, Hancocq-Quertier J, Paturiaux-Hanocq F, Nolan D P, Pays E

Abstract excerpt

In vitro differentiation of Trypanosoma brucei from the bloodstream to the procyclic form is efficiently induced by the combination of cold shock from 37 to 27 degrees C and the addition of citrate/cis-aconitate (CCA) to the incubation medium. Here it is reported that exposure of pleomorphic bloo...

Topics

Aconitic Acid
Animals
Citric Acid
Culture Media
Dihydrolipoamide Dehydrogenase
Genes, Protozoan
Glycosylphosphatidylinositol Diacylglycerol-Lyase
Hydrogen-Ion Concentration
Membrane Glycoproteins
Mice
Mutation
Phosphatidylinositol Diacylglycerol-Lyase
Protozoan Proteins
Trypanosoma brucei brucei
Type C Phospholipases
Variant Surface Glycoproteins, Trypanosoma

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PMID: 9662709
DOI: 10.1016/s0166-6851(98)00046-2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9662709-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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