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Article

Mild acid stress as a differentiation trigger in Trypanosoma brucei.

Molecular and biochemical parasitology - 1 Jun 1998

Rolin S, Hancocq-Quertier J, Paturiaux-Hanocq F, Nolan D P, Pays E

Abstract excerpt

In vitro differentiation of Trypanosoma brucei from the bloodstream to the procyclic form is efficiently induced by the combination of cold shock from 37 to 27 degrees C and the addition of citrate/cis-aconitate (CCA) to the incubation medium. Here it is reported that exposure of pleomorphic bloodstream trypanosomes to mild acidic conditions (pH 5.5 for 2 h at 37 degrees C) not only accelerated the process of...

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PMID: 9662709
DOI: 10.1016/s0166-6851(98)00046-2

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GPI

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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