Distortion of allele frequency distributions provides a test for recent population bottlenecks.

doi:10.1093/jhered/89.3.238

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Article

Distortion of allele frequency distributions provides a test for recent population bottlenecks.

The Journal of heredity - 1 Jan 2000

Luikart G, Allendorf F W, Cornuet J M, Sherwin W B

Abstract excerpt

We use population genetics theory and computer simulations to demonstrate that population bottlenecks cause a characteristic mode-shift distortion in the distribution of allele frequencies at selectively neutral loci. Bottlenecks cause alleles at low frequency (< 0.1) to become less abundant than...

Topics

Alleles
Animals
Gene Frequency
Humans
Models, Genetic

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