Thymic alterations in feline GM1 gangliosidosis.

doi:10.1016/s0165-2427(98)00113-5

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Article

Thymic alterations in feline GM1 gangliosidosis.

Veterinary immunology and immunopathology - 12 Jun 1998

Cox N R, Ewald S J, Morrison N E, Gentry A S, Schuler M, Baker H J

Abstract excerpt

GM1 gangliosidosis is an inherited metabolic disease characterized by progressive neurological deterioration with premature death seen in children and numerous animals, including cats. We have observed that thymuses from affected cats greater than seven months of age (GM1 mutant cats) show marked...

Topics

Adrenal Glands
Age Factors
Animals
Apoptosis
Cat Diseases
Cats
Cell Membrane
Child
Cholera Toxin
G(M1) Ganglioside
Gangliosidosis, GM1
Humans
Lymph Nodes
Mutation
T-Lymphocyte Subsets
Thymus Gland

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