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Article

A haplotype and linkage disequilibrium analysis of the hereditary hemochromatosis gene region.

Human genetics - 1 May 1998

Thomas W, Fullan A, Loeb D B, McClelland E E, Bacon B R, Wolff R K

Abstract excerpt

Hereditary hemochromatosis is a recessive disease of iron metabolism widely distributed among people of European descent. Most patients have inherited the causative mutation from a single ancestor. In the course of cloning the hemochromatosis gene, genotypes were generated for these samples at 43 microsatellite repeat markers that span the 6.5-Mb hemochromatosis gene region. The data used to reconstruct the...

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Identifiers

PMID: 9654199
DOI: 10.1007/s004390050734

Genes

HFE

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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A haplotype and linkage disequilibrium analysis of the hereditary hemochromatosis gene region.PMID 9654199Read ↗

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Haplotype analysis in Australian hemochromatosis patients: evidence for a predominant ancestral haplotype exclusively associated with hemochromatosis.Semantic proximity Read ↗

Anonymous marker loci within 400 kb of HLA-A generate haplotypes in linkage disequilibrium with the hemochromatosis gene (HFE)Semantic proximity Read ↗

The frequency of hemochromatosis-associated alleles is increased in British patients with sporadic porphyria cutanea tarda.Semantic proximity Read ↗

Haplotype analysis of the HFE gene: implications for the origins of hemochromatosis related mutations.Semantic proximity Read ↗

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