Article
Homeotic proboscipedia cell identity functions respond to cell signaling pathways along the proximo-distal axis.
The International journal of developmental biology - 1 Jan 1998
Boube M, Seroude L, Cribbs D L
Abstract excerpt
To better understand how the different cell identities composing a segment are attributed and coordinated under the control of a single homeotic selector gene, we examined dose-sensitive homeotic phenotypes associated with gain-of-function and loss-of-function mutations of the homeotic gene proboscipedia (pb; Hox-A2/-B2). We then employed dose-sensitive segment and cell identity phenotypes resulting from ectopic...
Topics
- Animals
- Body Patterning
- Cell Communication
- DNA-Binding Proteins
- Drosophila
- Drosophila Proteins
- GTPase-Activating Proteins
- Genes, Homeobox
- Homeodomain Proteins
- Insect Proteins
- Membrane Proteins