Article
The association between the IL-20-1723C→G allele on the 1q chromosome and psoriasis triggered or exacerbated by an upper respiratory tract infection in the Chinese Han population.
Dermatology (Basel, Switzerland) - 1 Feb 2011
Chen Xiao-Ying, Jin Li-Wei, Chen Ying-Wei, Tian Han, Yuan Wen-Tao, Niu Zhen-Min, Zhang Jing, Huang Wie, Zheng Jie
Abstract excerpt
BACKGROUND: Psoriasis is a cutaneous disorder of multifactorial etiology influenced by both genetic and environmental factors such as infection. METHODS: We conducted a genome analysis with 20 microsatellite markers spanning the long arm of chromosome 1 in 36 Chinese families with psoriasis and detected evidence for linkage at 1q21 with a nonparametric linkage score of 1.74, p=0.03, and 1q32 with one of 1.84,...
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