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Article

Identification of a human member of the Ly-49 multigene family

1 Jun 1998

Abstract excerpt

Three classes of multigene family-encoded receptors enable NK cells to discriminate between polymorphic MHC class I molecules: Ly-49 homodimers, CD94/NKG2 heterodimers and the killer cell inhibitory receptors (KIR). Of these, CD94/NKG2 has been characterized in both rodents and humans. In contrast, Ly-49 family members have hitherto been found only in rodents, and KIR molecules only in the human. In this report,...

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Identifiers

PMID: 9645365
DOI: 10.1002/(sici)1521-4141(199806)28:06<1839::aid-immu1839>3.0.co;2-e

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Research trail→

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Identification of a human member of the Ly-49 multigene familyPMID 9645365Read ↗

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Genomic Ly49A transgenes: basis of variegated Ly49A gene expression and identification of a critical regulatory element.Semantic proximity Read ↗

Class I MHC-binding characteristics of the 129/J Ly49 repertoire.Semantic proximity Read ↗

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