Role of the C-terminal tryptophan residue for the structure-function of the alphavirus capsid protein.

doi:10.1006/jmbi.1998.1817

Back to search

Article

Role of the C-terminal tryptophan residue for the structure-function of the alphavirus capsid protein.

Journal of molecular biology - 19 Jun 1998

Skoging U, Liljeström P

Abstract excerpt

The Semliki Forest virus capsid protein is a multifunctional protein which packages genomic RNA into nucleocapsid structures and binds to viral spike protein during budding. In addition, the capsid protein has an autoproteolytic activity whereby the C-terminal tryptophan is used as the substrate...

Topics

Capsid
Mutation
Semliki forest virus
Structure-Activity Relationship
Tryptophan

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.