Article
Immunoglobulin diversity, B-cell and antibody repertoire development in large farm animals.
Revue scientifique et technique (International Office of Epizootics) - 1 Apr 1998
Butler J E
Abstract excerpt
The B-cell lineage, the antibodies produced by these cells and the diversification of the antibody repertoire are essential for the health and survival of all mammals. Cattle, sheep, swine and horses, unlike rodents and primates, develop their antibody repertoire from a relatively small number of VH (variable heavy) genes of one or several families and cattle, sheep and horses use almost exclusively lambda-light...
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