Article
Pooled analysis of p53 mutations in hematological malignancies.
Human mutation - 1 Jan 1998
Prokocimer M, Unger R, Rennert H S, Rotter V, Rennert G
Abstract excerpt
A computerized database is described that contains information about 507 mutations in the p53 gene of hematologic tumors and corresponding cell lines. Analysis of these mutations indicated the following findings: First, mutational spectrum analysis in these tumors was found to be similar to the pattern found for other solid tumors. However, when the patterns of base substitutions were examined separately...
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