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Article

Aberrant p53 protein expression and function in a panel of hematopoietic cell lines with different p53 mutations.

European journal of haematology - 1 Apr 2009

Kamihira Shimeru, Terada Chiharu, Sasaki Daisuke, Yanagihara Katsunori, Tsukasaki Kunihiro, Hasegawa Hiroo, Yamada Yasuaki

Abstract excerpt

The p53 gene is one of the most important genes involved in carcinogenesis and its role in part has been clarified by research using cell lines. To know the comprehensive characteristics of 22 hematopoietic cell lines (T, 13 and non-T, nine lines), the relationship between p53 mutational status, its altered functioning, and its mRNA and protein levels were examined. p53 mutations were less frequent in T-cell...

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Source

Identifiers

PMID: 19220422
DOI: 10.1111/j.1600-0609.2009.01211.x

Genes

MDM2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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