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Article

Extensive, nonrandom diversity of excision footprints generated by Ds-like transposon Ascot-1 suggests new parallels with V(D)J recombination.

Molecular and cellular biology - 1 Jul 1998

Colot V, Haedens V, Rossignol J L

Abstract excerpt

Upon insertion, transposable elements can disrupt or alter gene function in various ways. Transposons moving through a cut-and-paste mechanism are in addition often mutagenic when excising because repair of the empty site seldom restores the original sequence. The characterization of numerous excision events in many eukaryotes indicates that transposon excision from a given site can generate a high degree of DNA...

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Identifiers

PMID: 9632817
DOI: 10.1128/MCB.18.7.4337
PMCID: PMC109017

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