Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The effects of macrolides on the expression of bacterial virulence mechanisms

1 May 1998

Abstract excerpt

Macrolides are unique among the various classes of antimicrobial agents because of the manner in which they interact with pathogens and the host immune system to produce a clinical response. Conventional efficacy explanations require the serum or tissue concentration of the macrolide to exceed the MIC of the macrolide to account for bacteriostatic activity. However, at concentrations below the MIC, there are...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antibiotic Resistance in Bacteria
Share to Antibiotics Pharmacokinetics and Efficacy
Share to Antimicrobial Resistance in Staphylococcus

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 9630404
DOI: 10.1093/jac/41.5.505

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The effects of macrolides on the expression of bacterial virulence mechanismsPMID 9630404Read ↗

Mechanisms of Action and Clinical Application of Macrolides as Immunomodulatory MedicationsSemantic proximity Read ↗

Development of new antituberculous drugs based on bacterial virulence factors interfering with host cytokine networksSemantic proximity Read ↗

Bacterial Survival Amidst an Immune Onslaught: The Contribution of the Staphylococcus aureus LeukotoxinsSemantic proximity Read ↗

Antimicrobial Effects of Antipyretics.Semantic proximity Read ↗

Bacterial Toxins as Pathogen Weapons Against PhagocytesSemantic proximity Read ↗

Regulatory Effects of Macrolides on Bacterial Virulence: Potential Role as Quorum-Sensing InhibitorsSemantic proximity Read ↗

Biotic acts of antibioticsSemantic proximity Read ↗

Advances in the macrolides and quinolones.Semantic proximity Read ↗

Novel Anti-virulence Compounds Disrupt Exotoxin Expression in MRSASemantic proximity Read ↗

The role of macrolides in asthma: current evidence and future directions.Semantic proximity Read ↗

Penicillin-binding proteins and the antibacterial effectiveness of beta-lactam antibiotics.Semantic proximity Read ↗

Long-Term Macrolides in Chronic Respiratory Diseases: Dusk or a New Dawn? A Narrative ReviewSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.