Molecular Basis of Tumor Progression: Mechanisms of Organ‐Specific Tumor Metastasis

Abstract excerpt

Tumor cell metastasis is an extremely complex process governed by many different classes of molecules with each class having a separate function. Metastasis is the result of multiple sequential steps and is a highly organized, nonrandom, and organ-selective process. Recent advances in tumor and molecular biology have permitted the identification of a variety of heterogeneous molecules governing invasion...

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