Correlation between cell cycle regulators and the immortalization and transformation of human breast epithelial cell lines.

doi:10.3892/ijo.13.1.65

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Article

Correlation between cell cycle regulators and the immortalization and transformation of human breast epithelial cell lines.

International journal of oncology - 1 Jul 1998

Salicioni A M, Russo I H, Russo J

Abstract excerpt

Cellular proliferation, essential for normal development, may result in neoplastic growth when the cell cycle clock is disrupted. In order to determine whether the protein expression of cell cycle regulators differs among normal, immortalized non-tumorigenic and malignant human breast epithelial...

Topics

Breast
Breast Neoplasms
Cell Cycle Proteins
Cell Division
Cell Transformation, Neoplastic
Cells, Cultured
Epithelial Cells
Female
Humans
Phenotype
Tumor Cells, Cultured

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