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Article

Altered Na+ and Li+ homeostasis in Saccharomyces cerevisiae cells expressing the bacterial cation antiporter NhaA.

Journal of bacteriology - 1 Jun 1998

Ros R, Montesinos C, Rimon A, Padan E, Serrano R

Abstract excerpt

The bacterial Na+ (Li+)/H+ antiporter NhaA has been expressed in the yeast Saccharomyces cerevisiae. NhaA was present in both the plasma membrane and internal membranes, and it conferred lithium but not sodium tolerance. In cells containing the yeast Ena1-4 (Na+, Li+) extrusion ATPase, the extra lithium tolerance conferred by NhaA was dependent on a functional vacuolar H+ ATPase and correlated with an increase of...

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Identifiers

PMID: 9620962
DOI: 10.1128/JB.180.12.3131-3136.1998
PMCID: PMC107813

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