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Article

Detection of reactive oxygen species (ROS) and apoptosis in human fragmented embryos

1 Apr 1998

Abstract excerpt

In human in-vitro fertilization (IVF)-embryo transfer, the in-vitro culture environment differs from in-vivo conditions in that the oxygen concentration is higher, and in such conditions the mouse embryos show a higher concentration of reactive oxygen species (ROS) in simple culture media. ROS are believed to cause damage to cell membranes and DNA fragmentation in somatic cells. This study was conducted to...

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PMID: 9619561
DOI: 10.1093/humrep/13.4.998

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