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Article

Programmed cell death and human embryo fragmentation

1 Jan 1996

Abstract excerpt

The quality of embryos produced by in-vitro fertilization (IVF) is variable. Many embryos contain unequal sized blastomeres and multiple cellular fragments. Embryos with excessive fragmentation have limited developmental potential both in vitro and in vivo. Histologically, some blastomeres of fragmented embryos resemble cells undergoing apoptosis as a result of programmed cell death (PCD). The objective of the...

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PMID: 9238664
DOI: 10.1093/molehr/2.2.93

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