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Article

The genetically programmed down-regulation of lactase in children.

Gastroenterology - 1 Jun 1998

Wang Y, Harvey C B, Hollox E J, Phillips A D, Poulter M, Clay P, Walker-Smith J A, Swallow D M

Abstract excerpt

BACKGROUND & AIMS: Intestinal lactase activity is high in all healthy human babies, but in adults a genetic polymorphism, which acts in cis to the lactase gene, determines high or low messenger RNA (mRNA) expression and activity (lactase persistence and nonpersistence, respectively). Our aim was to investigate the onset of expression of this polymorphism in children. METHODS: Activities were analyzed in relation...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 9609760
DOI: 10.1016/s0016-5085(98)70429-9

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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