Article
Pharmacogenomics of G protein-coupled receptor signaling: insights from health and disease.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2008
Thompson Miles D, Cole David E C, Jose Pedro A
Abstract excerpt
The identification and characterization of the processes of G protein-coupled receptor (GPCR) activation and inactivation have refined not only the study of the GPCRs but also the genomics of many accessory proteins necessary for these processes. This has accelerated progress in understanding the fundamental mechanisms involved in GPCR structure and function, including receptor transport to the membrane, ligand...
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