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Article

p53-Dependent and -independent responses to cisplatin in mouse testicular teratocarcinoma cells.

Proceedings of the National Academy of Sciences of the United States of America - 26 May 1998

Zamble D B, Jacks T, Lippard S J

Abstract excerpt

Testicular cancers respond favorably to chemotherapy with the platinum-containing drug cis-diamminedichloroplatinum(II) (cisplatin). One factor that could explain the efficacy of cisplatin is the low frequency of p53 mutations observed in this tumor type. The present study examines the p53-mediat...

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Share to Antineoplastic Agents
Share to Gene Expression Regulation, Neoplastic
Share to Genes, p53

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Neoplasms, Experimental

Share to Tumor Cells, Cultured

Share to Tumor Suppressor Protein p53

Source

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Identifiers

PMID: 9600935
DOI: 10.1073/pnas.95.11.6163
PMCID: PMC27612

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-9600935-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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