Article
Analysis of HLA-DQ alpha sequences for prenatal diagnosis in single fetal cells from maternal blood.
Human genetics - 1 Apr 1998
Sekizawa A, Taguchi A, Watanabe A, Kimura T, Saito H, Yanaihara T, Sato T
Abstract excerpt
We have extended a previously developed method that allows prenatal DNA diagnosis of female fetuses through the isolation of single nucleated erythrocytes from maternal blood by developing a method that can distinguish between maternal and fetal nucleated erythrocytes. Nucleated erythrocytes were separated by a density-gradient method and then collected by micromanipulation. Sex was determined after primer...
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