Article
Promoter sequence, expression, and fine chromosomal mapping of the human gene (MLP) encoding the MARCKS-like protein: identification of neighboring and linked polymorphic loci for MLP and MACS and use in the evaluation of human neural tube defects.
Genomics - 15 Apr 1998
Stumpo D J, Eddy R L, Haley L L, Sait S, Shows T B, Lai W S, Young W S, Speer M C, Dehejia A, Polymeropoulos M, Blackshear P J
Abstract excerpt
The MARCKS-like protein (MLP), also known as F52, MacMARCKS, or MARCKS-related protein, is a widely distributed substrate for protein kinase C (PKC). Recent studies using gene disruption in vivo have demonstrated the importance of both MARCKS and MLP to the development of the central nervous syst...
Topics
- Animals
- Base Sequence
- Brain Chemistry
- Calmodulin-Binding Proteins
- Chromosome Mapping
- Chromosomes, Human, Pair 1
- Cloning, Molecular
- DNA
- Gene Expression
- Genetic Linkage