Effects on larvicidal activity of single proline substitutions in alpha3 or alpha4 of the Bacillus thuringiensis Cry4B toxin.

doi:10.1080/15216549800201872

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Article

Effects on larvicidal activity of single proline substitutions in alpha3 or alpha4 of the Bacillus thuringiensis Cry4B toxin.

Biochemistry and molecular biology international - 1 Apr 1998

Uawithya P, Tuntitippawan T, Katzenmeier G, Panyim S, Angsuthanasombat C

Abstract excerpt

The possible role of alpha-helices 3 and 4 in toxicity of the dipteran-active Bacillus thuringiensis Cry4B delta-endotoxin was investigated by employing proline substitutions via site-directed mutagenesis. Similar to the wild-type Cry4B, the mutant toxins were over-expressed in Escherichia coli a...

Topics

Aedes
Amino Acid Sequence
Animals
Bacillus thuringiensis
Bacillus thuringiensis Toxins
Bacterial Proteins
Bacterial Toxins
Endotoxins
Escherichia coli
Hemolysin Proteins
Larva
Molecular Sequence Data

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mutagenesis, Site-Directed

Mutation

Pest Control, Biological

Proline

Protein Structure, Secondary

Recombinant Proteins

Source

Open in PubMed

Identifiers

PMID: 9584996
DOI: 10.1080/15216549800201872

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9584996-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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