The Effect of Class II Major Histocompatibility Complex Expression on Adherence of <i>Helicobacter pylori</i> and Induction of Apoptosis in Gastric Epithelial Cells: A Mechanism for T Helper Cell Type 1–mediated Damage

Abstract excerpt

Helicobacter pylori infection is associated with gastric epithelial damage, including apoptosis, ulceration, and cancer. Although bacterial factors and the host response are believed to contribute to gastric disease, no receptor has been identified that explains how the bacteria attach and signal the host cell to undergo apoptosis. Using H. pylori as "bait" to capture receptor proteins in solubilized membranes of...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Eosinophilic Esophagitis
• Share to Galectins and Cancer Biology
• Share to Helicobacter pylori-related gastroenterology studies