Prenatal onset of axonopathy in Dystonia musculorum mice.

doi:10.1002/(SICI)1520-6408(1998)22:2<160::AID-DVG5>3.0.CO;2-4

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Article

Prenatal onset of axonopathy in Dystonia musculorum mice.

Developmental genetics - 1 Jan 1998

Bernier G, Kothary R

Abstract excerpt

Dystonia musculorum (dt) is a recessive hereditary neuropathy of the mouse. Affected animals display loss of limb coordination and twisting of the trunk. Sensory nerve fibers of these mice are severely reduced in number, and the remaining fibers present numerous axonal swellings. The gene defecti...

Topics

Animals
Carrier Proteins
Cytoskeletal Proteins
Cytoskeleton
Dystonia Musculorum Deformans
Dystonin
Gene Expression Regulation, Developmental
Mice
Mice, Mutant Strains
Mutation
Nerve Tissue Proteins
Nervous System

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